Diversity as a Drive
Divèrsity creates the conditions for resilient farms, living landscapes and self-supporting communities.

Not just bìodiversity!

NoSelf Foundation works on diversity as a living condition for resilience: In soils, crops, farms, food systems, communities, knowledge and local economies, even (or espècially- in boardrooms). Nothing- no system- thrives in splendid isolation; resilience emerges from relationships, exchange, feedback and diversity.

We advocate diversity as a practical source of resilience. We connect biological science, farmer knowledge, local production and systems thinking to help farms and farming communities become less dependent, more adaptive and better able to thrive under environmental and economic pressure. We proliferate the beneficial use of “cell-free nucleic acid based” technologies into the agriculture of the developing world, using a string of peer-reviewed NoSelf scientific publications that started in 2014. (Abstract below).

We now focus on the Meditteranean Basin and presented at BioControl & BioStimulant Congress Cairo, September 2026, and spoke at the Morocco Tomato Conference Agadir, May 2026.

Diversity as a Service
Practical knowledge-based biological services that enable growers to rebuild resilience by restoring functional biological diversity in crop-production systems.

Applications of non-self/self nucleic acids are microbiome modulation (humans-), gut flora stabilizers (livestock-) and biostimulants (crops). These applications lead to the suppression of weeds, nematodes, fungi, insects, bacteria with their own extracellular, randomly fragmented or secreted selfDNA. For farmers and growers we promote Diversity as a Service; restoring cell-free nucleic acid diversity within the monocultures of high- and mid-tech horticulture, neutralizing autotoxicity (and even reversing the negative self-DNA inhibition effects-) in such vulnerable cultures and reducing all kinds of growers’ (hence communities’-) troubles.

Diversity as a Service enables farmers and growers to produce on-farm, for-farm and by-farm biocontrol and biostimulant systems to increase baseline biological (weed- and fungal-)resistance, improving their farm resilience with less long distance inputs. Especially in dry/hot areas. The biology is simple: Too much of “self” becomes toxic to the “self”, but lots of “non-self” are stimulating!

Noself Foundation “democratizes” the crop input practices by demonstrating that evidence based, scientifically evaluated, natural solutions can help farmers and grower in the developing world emancipate themselve with local solutions for local problems by local entities, quicker than the conventional bio-input companies can. Want to know more? Get in touch with our CEO Peter Jens. Chamber of Commerce, the Netherlands: 27303107 0000, address Arent Dirckszn Vosstraat 15, 2678CP De Lier, the Netherlands.

Donations welcome! We’ll provide our banking details upon request.

We originated out of No Self SRL, Italy, a groundbreaking multi-disciplined, international, research organisation, led by Professor Dr. Stefano Mazzoleni, University of Napoli, Federico II.

Abstract

The research for new products against pathogens, parasites and infesting species, in both agriculture and medicine, implies huge and increasing scientific, industrial and economic efforts. Traditional approaches are based on random screening procedures searching for bioactive compounds. However, the success of such methodologies in most cases has been strongly limited by side-effects of the potential new drugs, especially toxicity and pharmacological resistance. The use of nucleic acids in drug development has been introduced searching for target-specific effect. In addition, a recent discovery revealed that randomly fragmented extracellular self-DNA may act as highly species-specific inhibitory product for different species, suggesting an unprecedented use of nucleic acids for biological control. On this base, a new scenario of pharmacological and biocontrol applications is discussed.

Background IP on cell-free nucleotides: Patent 1 owned by No Self srl: The use of randomly fragmented genomic DNA. Patent 2 owned by No Self srl: The use of secreted DNA for specific inhibition. Patent 3 (pending-) owned by AND Biologicals BV: Use of nucleic acids as fertilizers and stimulants. Patent 4 owned by Koppert Biologicals BV: Mixing of DNA molecules, uses thereof as biological inhibitor and method for production. Agricultural animation: 3 minutes watching time, and worth it. Production protocols available on request.